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    Compounded · Dual PDE5
    Rated 4.6 by 113 RWell patients

    Ignite Melts

    Ignite combines Tadalafil + Sildenafil in one rapid-dissolving tablet — fast onset meets 36-hour staying power.

    Starting at $52/mo

    • Prescribed 100% online — no waiting rooms
    • US-licensed clinicians
    • Free 2-day shipping, discreetly packaged
    • Transparent pricing with no hidden fees

    Prescription products require an online consultation with a licensed clinician who will determine if a prescription is appropriate. Compounded medications are not FDA-approved or evaluated for safety, efficacy, or quality.

    Ignite Melts prescribed online by RWell
    Use your HSA/FSANo Hidden Fees24/7 MessagingFree Expedited ShippingNo Membership Fees
    Couple embracing after starting sexual health treatment

    How do Ignite melts work?

    • Ignite combines two PDE5 inhibitors in a single compounded tablet.
    • Sildenafil begins working within 30–60 minutes for reliable, on-demand performance.
    • Tadalafil provides a longer window of effectiveness — up to 36 hours — for spontaneous intimacy without time pressure.
    • Both compounds work by relaxing blood vessels and increasing blood flow, resulting in stronger, more reliable results.

    Formulation

    A compounded rapid-dissolving tablet that delivers the quick action of Sildenafil with the extended duration of Tadalafil.

    4 easy steps to get started

    1. 1

      Complete a short online intake

      Answer a secure health questionnaire about your history and goals — about 5–10 minutes.

    2. 2

      A licensed clinician reviews your intake

      A clinician licensed in your state reviews your answers, typically in under 4 hours.

    3. 3

      Compounded by a licensed pharmacy

      If appropriate, your compounded prescription is sent to our partner compounding pharmacy.

    4. 4

      Shipped discreetly to your door

      Your medication ships free with 2-day service in plain, unbranded packaging.

    Man completing his online telehealth visit at home

    Results that speak for themselves

    36hr

    Duration of effects

    The Tadalafil component provides up to 36 hours of effectiveness for spontaneous intimacy.¹

    30min

    Onset time

    The Sildenafil component begins working within 30–60 minutes for on-demand reliability.¹

    Dual PDE5 inhibitors

    Two proven compounds working synergistically for stronger, more reliable results.²

    Why choose RWell?

    Licensed Clinicians in 50 States + DC

    Every prescription is reviewed by a clinician licensed in your state, typically in under 4 hours.

    Compounded by licensed pharmacies

    Prepared by US-based compounding pharmacies to your prescribed strength.

    Discreet, expedited shipping

    Ships free with 2-day service in plain, unbranded packaging.

    Patient on a video call with a US-licensed RWell clinician

    Simple, transparent pricing

    No membership fees. No hidden charges. Auto-refills – cancel at least 48-hours prior to next refill.

    Every RWell Plan Includes:

    • No cost consultation
    • Free UPS 2nd Day Air
    • No membership or hidden fees
    • Unlimited messaging with your care team
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    10-count

    $125/mo

    $125 total

    One-time payment

    Get Started

    30-count

    Save 42%

    $73/mo

    $220 total

    One-time payment

    Get Started

    120-count

    Save 58%

    $52/mo

    $615 total

    One-time payment

    Get Started

    Dosing and safety

    Taken as needed, typically 30–60 minutes before sexual activity. Do not take more than one tablet in a 24-hour period. Your provider will determine the appropriate dosing based on your health profile.

    Possible side effects

    • Headache
    • Flushing
    • Indigestion
    • Nasal congestion
    • Dizziness

    Rare but serious effects include sudden vision or hearing impairments and priapism (erection lasting more than 4 hours). Seek immediate medical attention for these symptoms. Do not take with nitrates or certain heart medications.

    Explore other sexual health treatments

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    Patient reviews

    What patients say

    4.8290 reviews
    • Respondwell has been great. They've also been really easy to work with – I needed to change my shipment schedule and they took care of it without any hassle.
      M.M. — verified patient
      5.0
    • Started seeing progress right away. Really happy with how things are going so far!
      J.C. — verified patient
      5.0
    • No complaints at all. Everything was explained clearly, the doctor was great, and my order showed up without any issues.
      D.K. — verified patient
      5.0
    • Very pleased so far. The whole experience has been easy and everything went exactly as expected.
      N.H. — verified patient
      5.0
    • Honestly, everything has been easy. Good communication, good experience with the doctor, and no issues getting my medication.
      A.Z. — verified patient
      5.0
    • Overall I've had a good experience. Shipping has been reliable and I've been very happy with everything.
      F.Y. — verified patient
      4.3

    Reviews are unedited patient feedback. Star ratings are an aggregate of individual ratings across three categories: medical care and provider interactions, customer service and communication, and delivery experience. Shown with initials only for privacy. Individual results vary and are not guaranteed.

    Frequently asked questions

    Ignite combines Tadalafil and Sildenafil in one compounded tablet, giving you the fast onset of Sildenafil with the long-lasting effects of Tadalafil. It increases blood flow when aroused, providing reliable performance.

    The effects can last up to 36 hours due to the Tadalafil component, while the Sildenafil provides quick onset — typically within 30-60 minutes. This gives you flexibility without needing to time your dose precisely.

    Ignite is safe for most men when used as directed. It's not recommended for those taking nitrates or certain heart medications. Our providers will review your health history to ensure it's appropriate for you.

    Common side effects include headache, flushing, indigestion, nasal congestion, and dizziness. Rare but serious effects include sudden vision or hearing impairments and priapism (erection lasting more than 4 hours). Seek immediate medical attention for these symptoms.

    Still have questions?

    Get Started

    Ready to feel confident again?

    Complete a quick health intake — your provider reviews within hours. No waiting rooms, no awkward conversations. Just effective treatment, delivered to your door.

    Get Started

    *Ignite is a compounded medication containing Tadalafil and Sildenafil. Compounded medications are not FDA-approved and have not undergone FDA premarket review for safety, effectiveness, or quality. This product is not associated with any branded PDE5 inhibitor. Individual results may vary.

    Clinical References

    1 Lee M. (2011). Focus on phosphodiesterase inhibitors for the treatment of erectile dysfunction in older men. Clin Ther. 33(11):1590–1608.

    2 Corbin JD, Francis SH. (2002). Pharmacology of phosphodiesterase-5 inhibitors. Int J Clin Pract. 56(6):453–459.

    ED Treatment is not offered in the following states: South Carolina.

    Compounded medications are prepared by licensed compounding pharmacies and are not FDA-approved. The FDA does not evaluate compounded medications for safety, efficacy, or quality. Prescription products require an online consultation with a licensed clinician who will determine if a prescription is appropriate. Individual results vary. This page is for informational purposes only and is not medical advice.