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    Hormone Therapy · Oral
    Rated 4.8 by 89 RWell patients

    Enclomiphene

    Enclomiphene stimulates your natural testosterone production — no injections, no shutdown, fertility preserved.

    Starting at $110/mo

    • Prescribed 100% online — no waiting rooms
    • US-licensed clinicians
    • Free 2-day shipping, discreetly packaged
    • Transparent pricing with no hidden fees

    Prescription products require an online consultation with a licensed clinician who will determine if a prescription is appropriate. Compounded medications are not FDA-approved or evaluated for safety, efficacy, or quality.

    Enclomiphene prescribed online by RWell
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    Man lifting weights after starting hormone therapy

    How does Enclomiphene work?

    • Enclomiphene blocks estrogen receptors in the brain, signaling your body to produce more LH and FSH.
    • These hormones then stimulate your testes to produce more testosterone naturally.

    Formulation

    A daily oral tablet that signals your body to produce more testosterone on its own — without replacing it.

    4 easy steps to get started

    1. 1

      Complete a short online intake

      Answer a secure health questionnaire about your history and goals — about 5–10 minutes.

    2. 2

      Get your labs drawn

      We order convenient lab work so your clinician can confirm you're a candidate before prescribing.

    3. 3

      Compounded by a licensed pharmacy

      If appropriate, your prescription is sent to our partner compounding pharmacy.

    4. 4

      Shipped discreetly to your door

      Your medication ships free with 2-day service in plain, unbranded packaging.

    Father with his child after restoring his energy with hormone therapy

    Results that speak for themselves

    200%+

    Increase in LH levels

    Clinical studies show enclomiphene significantly increases luteinizing hormone, stimulating natural T production.¹

    100%

    Fertility preservation

    Unlike TRT, enclomiphene maintains sperm production and testicular function throughout treatment.²

    0

    Injections required

    Simple daily oral tablet — no needles, no syringes, no clinic visits for injections.

    Why choose RWell?

    Licensed Clinicians in 50 States + DC

    Every prescription is reviewed by a clinician licensed in your state, typically in under 4 hours.

    Compounded by licensed pharmacies

    Prepared by US-based compounding pharmacies to your prescribed strength.

    Discreet, expedited shipping

    Ships free with 2-day service in plain, unbranded packaging.

    Patient on a video call with a US-licensed RWell clinician
    4 Easy Steps

    How To Get Started

    Rapid labs. Accurate diagnosis. Legit doctors.
    No guesswork — and no video visit required.

    1
    $69

    Order Your Labs

    Comprehensive men's health panel:

    2

    Get Drawn at Quest

    Walk into any Quest Diagnostics location nationwide. No appointment needed.

    Find a Quest location
    3

    Results in ~5 Days

    If your testosterone level qualifies, we email + text your intake paperwork. No video visit required. 10 minutes, on your phone.

    4

    Meds Within a Week

    Prescription written by a licensed physician and shipped discreetly to your door.

    Auto-refills – cancel at least 48-hours prior to next refill

    Founders Pricing — First 30 Patients
    Today
    $69
    Initial Labs
    First Month
    $110
    If qualified
    After
    $130
    per month

    Locked-in rate for life. Limited to the first 30 enrolled.

    Order labs today · Results in (about) 5 days · No video visit required
    Online lab ordering not yet available in NY, NJ or RI.

    Dosing and safety

    Typically taken as a daily oral tablet. Your provider will determine the appropriate dose based on your blood work and response to treatment.

    Possible side effects

    • Headache
    • Hot flashes (uncommon)
    • Mood changes
    • Visual disturbances (rare)

    Explore other hormone therapy treatments

    More drive. More you.

    Patient reviews

    What patients say

    4.8290 reviews
    • Respondwell has been great. They've also been really easy to work with – I needed to change my shipment schedule and they took care of it without any hassle.
      M.M. — verified patient
      5.0
    • Started seeing progress right away. Really happy with how things are going so far!
      J.C. — verified patient
      5.0
    • No complaints at all. Everything was explained clearly, the doctor was great, and my order showed up without any issues.
      D.K. — verified patient
      5.0
    • Very pleased so far. The whole experience has been easy and everything went exactly as expected.
      N.H. — verified patient
      5.0
    • Honestly, everything has been easy. Good communication, good experience with the doctor, and no issues getting my medication.
      A.Z. — verified patient
      5.0
    • Overall I've had a good experience. Shipping has been reliable and I've been very happy with everything.
      F.Y. — verified patient
      4.3
    Read all patient reviews

    Reviews are unedited patient feedback. Star ratings are an aggregate of individual ratings across three categories: medical care and provider interactions, customer service and communication, and delivery experience. Shown with initials only for privacy. Individual results vary and are not guaranteed.

    Frequently asked questions

    Clomid (clomiphene citrate) is FDA-approved (for certain female fertility indications). Chemically, clomiphene citrate isn't one single molecule — it's a blend of two geometric isomers: enclomiphene and zuclomiphene. Enclomiphene is the isomer most often described as the more anti-estrogenic component. In men with secondary hypogonadism, it has been studied for its ability to increase LH and FSH, which can help the testes produce more of the body's own testosterone. Zuclomiphene is the other half of clomiphene citrate. It's commonly described as having more estrogenic (agonist-leaning) activity and staying in the body longer, which is one reason some clinician protocols prefer enclomiphene-only approaches when the goal is a 'cleaner' anti-estrogen signal. Important distinction: While clomiphene citrate (the mixture) is FDA-approved for specific uses, enclomiphene by itself is not FDA-approved as a standalone drug. Kim ED, McCullough A, Kaminetsky J. Oral enclomiphene citrate raises testosterone and preserves sperm counts in obese hypogonadal men, unlike topical testosterone: restoration instead of replacement. BJU Int. 2016;117(4):677-685. https://doi.org/10.1111/bju.13337 Earl JA, Kim ED. Enclomiphene citrate: a treatment that maintains fertility in men with secondary hypogonadism. Expert Rev Endocrinol Metab. 2019;14(3):157-165.

    Enclomiphene is intended for men who want to boost their natural testosterone production while preserving fertility. It's particularly popular among younger men and those who prefer an oral medication over injections.

    Unlike traditional testosterone replacement therapy (TRT), which supplies external testosterone, Enclomiphene stimulates your body to produce more testosterone naturally, preserving fertility and testicular function.

    Yes. Enclomiphene works by prompting your own hormone production rather than replacing it, so sperm production continues.

    Still have questions?

    No runaround. No needles. Fertility-friendly.

    Quick intake → included labs → licensed provider review. Fertility-supportive option for eligible patients. (Rx only if clinically appropriate).

    *Enclomiphene citrate is not FDA-approved as a standalone drug. It is the trans-isomer of clomiphene citrate, which is FDA-approved for certain female fertility indications. Compounded enclomiphene has not been reviewed by the FDA for safety, quality, or efficacy. Clinical references below reflect published research on enclomiphene in male hypogonadism.

    Clinical References

    1 Kim ED, et al. (2014). Enclomiphene citrate stimulates testosterone production while preventing oligospermia: a randomized phase II clinical trial. Fertil Steril. 102(3):720–727. https://pubmed.ncbi.nlm.nih.gov/25044085/

    2 Saffati, G., et al. (2024). Safety and efficacy of enclomiphene and clomiphene for hypogonadal men. Cureus. https://pmc.ncbi.nlm.nih.gov/articles/PMC11491226/

    3 Rodriguez, K. M., & Pastuszak, A. W. (2016). Enclomiphene citrate for the treatment of secondary male hypogonadism. Expert Opinion on Pharmacotherapy. https://pmc.ncbi.nlm.nih.gov/articles/PMC5009465/

    4 Wiehle, R. D., et al. (2014). A randomized phase II clinical trial comparing enclomiphene citrate and testosterone gel in men with secondary hypogonadism. https://pubmed.ncbi.nlm.nih.gov/25044085/

    5 Wiehle, R. D., et al. (2013). Testosterone restoration by enclomiphene citrate in men with secondary hypogonadism. https://pubmed.ncbi.nlm.nih.gov/23875626/

    Compounded medications are prepared by licensed compounding pharmacies and are not FDA-approved. The FDA does not evaluate compounded medications for safety, efficacy, or quality. Prescription products require an online consultation with a licensed clinician who will determine if a prescription is appropriate. Individual results vary. This page is for informational purposes only and is not medical advice.